Title 1 Response variability to high rates of electric stimulation in retinal ganglion cells
نویسندگان
چکیده
1 Response variability to high rates of electric stimulation in retinal ganglion cells. 2 3 Authors 4 Changsi Cai 2, 3 5 Qiushi Ren, PhD 6 Neal Desai, MD 7 Joseph Rizzo III, MD 2, 4 8 Shelley Fried, PhD 3 9 10 Affiliation 11 1. Institute for Laser Medicine and Bio-Photonics, Department of Biomedical 12 Engineering, Shanghai Jiao-Tong University, Shanghai, China 13 2. Center for Innovative Visual Rehabilitation, Boston Veterans Administration 14 Healthcare System, Boston, MA 15 3. Department of Neurosurgery, Massachusetts General Hospital and Harvard 16 Medical School, Boston, MA 17 4. Department of NeuroOphthalmology, Massachusetts Eye and Ear Infirmary, 18 Boston, MA 19 20 21 Running Head 22 Response variability to electric stimulation 23 24 Corresponding Author 25 Shelley I. Fried, PhD 26 Massachusetts General Hospital / Harvard Medical School 27 165 Cambridge Street – Simches 3600 28 Boston, MA 02114 29 email: [email protected] 30 31
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Response variability to high rates of electric stimulation in retinal ganglion cells.
To improve the quality of prosthetic vision, it is important to understand how retinal neurons respond to electric stimulation. Previous studies present conflicting reports as to the maximum rate at which retinal ganglion cells can "follow" pulse trains, i.e., generate one spike for each pulse of the train. In the present study, we measured the response of 5 different types of rabbit retinal ga...
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